We already discussed in a previous article what MSM is and what its role is in our body.

In the following lines we will detail the keys to its operation, as well as its important properties, in order to make the importance of this organic sulfur for our general health and well-being understandable to the general population.


The functions of MSM emanate from its ability to penetrate inside the cells, generating antioxidant and anti-inflammatory consequences (Berardesca, Cameli and Cavalloti, 2018). There are still many studies that completely decipher its operation, but from the research carried out, it has been found that MSM has, in our body, a marked influence such as (Butawan, Benjamin and Bloomer, 2017; Kim et al., 2016):

  • Immune System Regulator: The function of our immune system is to protect us from all kinds of germs, toxins, viruses and bacteria. However, excessive activation of our defense system can lead to harmful effects for the body, both in the short and medium and long term. The MSM, precisely, acts as a regulator of the organism, avoiding possible excesses in the defensive processes of our body.
  • Cell oxidation reducer: Every day, our body suffers the effect of free radicals, which are reactive oxygen species produced by our own cells. If these free radicals accumulate in excess, they cause obvious damage to our tissues, leading to accelerated and early aging (which is nothing more than cellular oxidation). Studies show that MSM could minimize the damaging actions of free radicals and slow down the rate of cell oxidation.
  • Inflammation controller: Studies indicate that MSM inhibits the synthesis of chemical structures that are responsible for many of the body’s inflammatory processes, which could greatly prevent the acceleration of the immune system, an acceleration that would become harmful and harmful to the body’s defense system. .
  • Sulfur Gift: The donation made by the MSM of its sulfur atoms to other tissues and components found in our body, favors and facilitates its normal functioning. It is also considered that some amino acids (such as methionine and cysteine) take advantage of this sulfur to make up important and necessary proteins for the optimal growth of new cellular tissues.

Based on this, we can say that MSM, as a natural sulfur compound, is a vital substance for our body, since it intervenes in the formation of collagen and amino acids – which, in turn, are essential for the development of proteins, necessary for the formation and maintenance of bones and hair, as we explained in a previous article on MSM in Algamania. Likewise, it stimulates in our body the formation of enzymes and active proteins, something essential in the transport of nutrients (Berardesca, Cameli and Cavalloti, 2018).


algas marinasAt the functional level, sulfur is much more than a simple protein-binding element, since it is part of the extracellular matrix (Notarnicola, Maccagnano, Moretti and Pesce, 2016).

In a simple way, we could say that the connective tissue in which cells are located is much more than their support and union. Based on this, sulfur is essential for nutrition and cell cleaning, for the transport of nutrients, electrolytes, hormones, chemical signals and waste, being able to affirm that it serves as an intracellular communication network, which thanks to sulfur remains elastic.

Furthermore, research indicates that sulfur behaves as a flexible link between proteins and connective tissue, as it improves the permeability of the cell membrane.

Thus, the MSM, by balancing the pressure on both sides of the cell, manages to protect it from oxidative stress. If sulfur is lacking, the cell’s membrane hardens and, being less flexible, it may be more difficult for it to introduce nutrients, allow oxygen, or eliminate cellular debris (Van der Merwe and Bloomer, 2016). So much so, that the new cells that replace those that die without sulfur, will be built with rigid and poorly functional or operational membranes, which would facilitate their degeneration and oxidation (Miller, 2018).

Consequently, the importance of sulfur (and, therefore, the consumption of MSM) is postulated, since it can contribute to cell nutrition and cleaning, with an important antioxidant effect and pH balance, protecting the cell from free radicals , as we have said, which would promote cell and structures recovery of damaged tissue (Magnuson, Appleton and Ames, 2017). Aspects to keep in mind in the face of many of the diseases that we all know cause many annual deaths.


  1. Protective effect of mucous membranes against parasites, toxins, waste substances, etc.
  2. Natural lubricating effect of the joints, improving mobility and normal functioning.
  3. Detoxifying effect of heavy metals, dissolves compounds by inactivating them or helping to excrete it.
  4. Increased permeability of the cell membrane, making it easier for nutrients to enter and improving the excretion of toxins into the extracellular fluid and lymphatic system.
  5. Improving the flexibility of tissues and stimulating the repair of damaged skin, because it is responsible for flexible links between cells.
  6. Antioxidant effect of free radicals, it is also, like Astaxanthin, one of the few antioxidants capable of crossing the blood-brain barrier, which helps prevent and repair damage to brain cells.
  7. Inhibits inflammation and pain, reduces muscle spasms and smoothes scar tissue.
  8. Anti-allergenic effect, it has been found to be a great help for all kinds of allergies, including food, due to its ability to lower inflammation and eliminate toxins.
  9. It helps to increase the entrance of glucose to the cells and, in this way, avoids stress to the pancreas.
  10. Sulfur is necessary for the production of Collagen and Keratin, main components in the skin, hair and nails.
  11. At high concentrations, it can work to deworm the body, cleansing and detoxifying it.

In addition to the aforementioned, MSM is considered a great ally against pain, as it contributes to alleviating and treating various ailments, such as (Kim, Kim, Lim and Baek, 2019): chronic pain, acne, arthritis, tendinitis, bursitis and rheumatism, fibromyalgia, carpal tunnel syndrome, muscle aches, cramps, osteoarthritis, tenosynovitis, chronic fatigue, and headaches and migraines.

In addition to having been very effective in combating allergies, how bothersome they can be for the population sensitive to certain elements (Notarnicola, Maccagnano, Moretti and Pesce, 2016).

At Algamania we know the importance of taking a good MSM supplement, thanks to all the properties that organic sulfur has for our body, and you can buy it directly in our Online Store

In a future article we will delve into, in more detail, the benefits that supplementation with MSM can provide us.


Anh, H., Kim, J., Lee, M.J., Kim Y.J. and Cho, Y.W. (2015). Methylsulfonylmethane inhibits NLRP3 inflammasome activation. Cytokine, 71 (2), 223-231.

Berardesca, E., Cameli, N. and Cavalloti, C. (2018). Combined effects of silymarin and methylsulfonylmethane in the management of rosacea: clinical and instrumental evaluation. Journal of Cosmet. Dermatol., 7 (1), 8-14.

Butawan, M., Benjamin, R.L. and Bloomer, R.J. (2017). Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. Nutrients, 9 (3), 290-297.

Debbi, E.M., Agar, G., Fichman, G. and Ziv, Y.B. (2019). Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study. BMC Complementary and Alternative Medicine, 11 (1): 50-57.

Kim, L.S. et al. (2016). Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage, 14 (3), 286-294.

Kim, Y.H., Kim, D.W., Lim, H. and Baek, D.Y. (2019). The anti-inflammatory effects of Methylsulfonylmethane on lipopolysaccharide- Induced Inflammatory Responses in Murine Macrophages. Biol. Pharm. Bull., 32 (4), 651-656.

Magnuson, B.A., Appleton, J. and Ames, G.B. (2017). Pharmacokinetics and distribution of {35S} methylsulfonylmethane following oral administration to rats. Journal of Agric. Food Chem., 55 (3), 1033-1038.

Miller, L.E., (2018). Methylsulfonylmethane decrease inflammatory response to tumor necrosi factor-a in cardiac cells. American Journal Cardiovasc. Dis., 8 (3), 31-38.

Notarnicola, A., Maccagnano, G., Moretti, L. and Pesce, L. (2016). Methylsulfonylmethane and boswellic acids versus glucosamine sulfate in the treatment of knee arthritis: Randomized trial. Int. J. Immunopathol. Pharmacol., 29 (1), 140-146.

Van der Merwe, M. and Bloomer, R.J. (2016). The influence of Methylsulfonylmethane on Inflammation – Associated Cytokine Release before and following Strenuous Exercise. Journal of Sports Medicine, 2016 (1), 1-9.

Write a comment

Your email address will not be published. Required fields are marked *